Positive feedback regulation
Rodolphe Sepulchre, University of Cambridge, UK
Abstract:
Learning and adaptation are rooted in the theory of negative feedback regulation. This talk will emphasize the critical role of positive feedback in the regulation of neuronal rhythms. I will argue that the role of positive feedback is poorly understood, both in neuronal modelling and in control theory. Illustrations will be provided at different scales, from single cell models to large neuronal networks, revisiting several classical models of bursting, half-center oscillators, and thalamo-cortical brain states in the light of neuromodulation. I will propose that a theory of mixed feedback is necessary to design learning and adaptation mechanisms across scales.